Evaluation and comparison of anti-Candida effect of heat cure polymethylmethacrylate resin enforced with silver nanoparticles and conventional heat cure resins: An in vitro study.

Recent years have been dominated by research in nano science. Dentistry is no exception and there is increased research on nanoparticles in dentistry. Complete dentures increase the carriage of Candida in healthy patients, and the proliferation of C. albicans can be associated with denture-induced stomatitis. Purpose: To evaluate the anti-Candida effect of heat cure denture base resins reinforced with Ag° in the ratio of 4:1, 3:1, 2:1 (Groups B, C, and D, respectively) to the weight of denture base resins. Materials and Methods: Ag° were synthesized by chemical reduction method, incorporated into the polymer powder according to the ratio for each group, subjected to polymerization and microbial assay was calculated for the reference C. albicans strains by agar diffusion method for the incubation period of 24 h. Results: Group D showed multifold decrease in the colony-forming units. Conclusion: The antimicrobial effect of silver could be used vividly in the denture base for immunocompromised and geriatric patients.

Surgical Treatment of Spinal Plasma Cell Tumors

OBJECTIVE: The purpose of this study is to review the cases of spinal plasma cell tumors treated in our department with regard to presenting symptoms and signs, diagnostic investigations, extent of surgical interventions, complications, survival time and influence on the quality of life. METHODS: In a retrospective study, twelve spinal plasma cell tumor patients who underwent surgery were evaluated between Oct. 1991 and Dec. 2000. Clinical staging system was evaluated by Durie-Salmon Staging System. RESULTS: There were multiple myeloma in nine and solitary plasmacytoma in three patients, six men and six women and aged 38 to 69 years(mean 56.8 years). The locations of the lesions were two cervical, two cervico-thoracic, three thoracic, one thoraco-lumbar, three lumbar and one sacral. The most common initial presenting symptom and sign were local pain and motor weakness. Radiographs showed pathologic compression fracture in six and the MRI finding were cortical infolding, focal to diffuse patterns of low-signal on T1WI, high signal intensity on T2WI, and variable of enhancement on Gadolinium enhanced T1W1. Sixteen operations were performed. and the adjuvant theraphy included radiotheraphy, chemotheraphy(combined oral melphalan and predinisone), and autologous PBST(peripheral blood stem cell transplantation). The follow-up period was three to sixty months(mean 27.0 months). The mean Karnofsky scale score was changed from 54.5 to 73.3 after follow up. One patient died of pulmonary metastasis and sepsis. CONCLUSION: Our experience suggests that treatment of spinal plasma cell tumor may be rewarding.

Treatment of Chronic Osetomyelitis by Saucerization and Gentamicin / 대한정형외과학회잡지

Chronic osteomyelitis continue to be a therapeutic challenge. The osteomyelitis also implies chronic ischemia of the diseased bone ; thus systemic antibiotic treatment may not be as effective as we want. In 1972, Klemm developed a new procedure to supplement saucerization in the treatment of chronic osteomyelitis, alternative to irrigation and suction-drainage, i.e., Gentamicin-PMMA Beads. The authors analysed 35cases of the chronic osteomyelitis which were admitted and treated by sauceriztion and Gentamicin-PMMA Beads in Department of Orthopaedic Surgery, Korea Veterans Hospital from Aug. 1984 to Jan. 1988.